![]() However, I understand that, because of the gradually increasing pension age, she cannot apply for a bus pass until next year.OTIS Credit: Steve Russell/ Toronto Star via Getty Images Singer, songwriter, record producer, and dancer Catherine, better known as Kate, Bush CBE is 65 years young today. If you don’t understand, or don’t wish to comply with, the conventions for commenting on weekend prize puzzles then save yourself a lot of trouble and don’t leave a comment. In all cases the administrator’s decision is final. ![]() ![]() Offending comments may be redacted or, in extreme cases, deleted. ![]() Please read these instructions carefully – they are not subject to debate or discussion. How one might describe fondue because of it’s main ingredient.Ģ6d Box, for example (4) or Box, for example (4)Ī double definition – the first is a synonym of box as a type of container.Ĭould new readers please read the Welcome post and the FAQ before posting comments or asking questions about the site.Īs this is a Prize crossword, please don’t put any ANSWERS, whether WHOLE, PARTIAL or INCORRECT, or any ALTERNATIVE CLUES OR HINTS in your comment. Guess a five letter country (that just happens to be in Africa) followed by a four letter Asian country with its letter R deleted (not right).Ī lurker (in) found in the last two words of the clue.ġ9d Male blocks a more ghastly suitor (7)Ī from the clue followed by the single letter for Male inserted into (blocks) a comparative form (more) of a synonym of ghastly. The smallest unit of currency (coin) almost everywhere except the UK and our favourite two letters equivalent to on.ġ4d German physicist well meaning, originally (3)Ī two letter interjection equivalent to well and the first letter (originally) of Meaning.ġ7d African country, Asian country not right (8) How a golfer might ‘approach’ playing a shot when his or her ball is in a (sand) trap.Ģ3a Non-alcoholic drink, abundance found in last few bars? (5,4)Ī synonym of abundance contained by (found in) the term for the last few bars (of a piece of music).Ģ5a Pertinent European directive, ultimately (7)Ī European from a particular country and the last letter (ultimately) of directivE.Ī synonym of rush and a two letter synonym of running (as in working).ġd Busy cooks entertaining party served up alcoholic dessert (8)Īn anagram (cooks) of BUSY containing (entertaining) the reversal (served up) of a type of (usually very formal) party.ģd Pig stuffed with first of trimmings, cook meaty snack (3,3)Ī type of male pig (one that has been ‘fixed’) containing (stuffed with) all of the first letter of Trimmings and a synonym of cook. One of the sets of two well known sets of books placed (written) after an anagram (novel) of READY.ġ1a French city has better device for photographer (4,3)Ī city in Northern France and a verbal synonym of better.Ī homophone (for the audience) of a synonym of space.ġ6a Defensive strategy - of golfer in trap? (6,9) Another useful page is Wolves in Sheep’s Clothing, which features words with meanings that are not always immediately obvious.Ī full review of this puzzle will be published after the closing date for submissions.ħa Books written after novel ready - long time ago (4,3) Where the hint describes a construct as “usual” this means that more help can be found in The Usual Suspects, which gives a number of the elements commonly used in the wordplay. Most of the terms used in these hints are explained in the Glossary and examples are available by clicking on the entry under “See also”. Sunday Telegraph Cryptic No 3223 (Hints) Hints and tips by SenfĪ very good palindromic Sunday morning from Winnipeg, where, with apparently serious discussions on UFOs taking place to the South of us, it was gratifying to be advised that Manitoba’s vast and sparsely populated wilderness, along with its resilient and resourceful communities, position it as a province, second only to Nova Scotia, most likely to survive an alien invasion with an alien survivability score of 7.50/10.įor me, etc, Dada more friendly than usual today although the grid is somewhat strange, with five anagrams (three partials), three lurkers, and two homophones, – all in a very asymmetric 31 clues with 16 hints ‘sprinkled’ throughout the grid, you should be able to get the checkers to enable the solving of the unhinted clues.Ĭandidates for favourite – 16a, 28a, 21d, 23d, and 24d.Īs is usual for the weekend prize crosswords, a number of the more difficult clues have been selected and hints provided for them.ĭon’t forget to follow the instructions in RED at the bottom of the hints!
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Such states are in a better position to consider the cost-effectiveness and reliability of the new tests and to either limit or extend them to the detection of particular fetal pathologies in certain categories of pregnant women. According to Löwy, the variability in the implementation of NIPT across the world is because of the existent state-sponsored testing programs for trisomy 21. However, in some other countries, the test is paid for by private or public insurers, who may choose to restrict its use to the detection of certain pathologies among categories of pregnant women at higher risk of fetal anomalies. ![]() In some countries, such as Brazil, extended versions of this test are available only at private health facilities, thereby limiting its use to women who can afford it out of their own pockets. Some of these chromosomal alterations lead to pathologies with varying seriousness. Based on the versions, these tests can detect a variable number of more or less rare anomalies (only trisomy 21, or also trisomy 13 and 18, or also rare trisomies, or even chromosomal microdeletions, etc.) with varying degrees of reliability. The implementation of NIPT differs from country to country. The latter, requires invasive sampling, such as amniocentesis or trophoblast biopsy, thereby carrying a small risk of miscarriage. Because of the lower false-positive results of NIPT, it offers the advantage of reducing the need for a diagnostic test. Positive results must be confirmed by a diagnostic test, such as the fetal karyotype. This test involves the analysis of cell-free fetal DNA circulating in pregnant women’s blood and provides reliable (fewer false positives and false negatives) results earlier in the pregnancy. However, previous tests for testing and diagnosing fetal anomalies have not been patented and are less expensive.ĭespite its high price, NIPT has been a commercial success because of its several advantages over conventional testing for trisomy 21, such as serum markers 1 and ultrasound scans, or a combination of both. These companies have applied for patents in various countries. ![]() Since its launch in 2011, NIPT has been commercially available in many countries, which is mainly due to the driving force of biotechnology companies manufacturing these tests. Non-invasive prenatal testing (NIPT) is a newly developed genetic test designed to detect chromosomal anomalies in fetuses. ![]() Non-invasive prenatal testing (NIPT) regulation prenatal screening informed consent France ethics reproductive autonomy 1. The analysis reveals that the regulations, consistent with that applied to other prenatal screening techniques, fail to take proper account of the following problems posed by NIPT: the continuing increase in the number of abnormalities detected in fetuses, the context of mounting pressure from the manufacturers, and the challenges involved in providing pregnant women with quality information that preserves their reproductive autonomy. In addition, this article evaluates the effectiveness of the regulatory framework in addressing the ethical and social issues raised by this technique from a legal and sociological perspective. This article examines the regulation of the screening of fetal abnormalities in France before and after the implementation of the new technique of non-invasive prenatal testing (NIPT) in 2013. This is an open access article distributed under the conditions of the Creative Commons by Attribution License, which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is correctly cited. The Regulation of Non-Invasive Prenatal Testing (NIPT) in France: Continuity and Changes in the Development of Prenatal Testing. Recommended citation: Vassy C, Brunet L, Noiville C. Received: Septem| Accepted: Febru| Published: February 25, 2022 ![]() Special Issue: Policy Issues in Prenatal and Neonatal Testing, Counseling, and Decision-Making Institut des Sciences Juridiques et Philosophiques de La Sorbonne, Université Paris 1 CNRS, UMR 8103, 1 rue de la glacière, 75013 Paris, FranceĪcademic Editors: Diane B. Université Sorbonne Paris Nord, IRIS, EHESS, CNRS, UMR 8156, Inserm U997, 74 rue Marcel Cachin, 93 000 Bobigny, France Carine Vassy 1,*, Laurence Brunet 2, Christine Noiville 2 ![]() “If money is not your servant, it will be your master.” - Francis Bacon “Time you enjoy wasting is not wasted time.” – John Lennon “Some day you will be old enough to start reading fairy tales again.” - C.S. “It’s harder to be kind than clever.” - Lawrence Gise “Just because you trust someone with your life doesn’t mean you should trust them with your money.” - Iain Banks “Criticism is a privilege that you earn - it shouldn’t be your opening move in an interaction.” - Malcolm Gladwell “Don’t stress too much about life because no one is getting out alive.” “When you don’t like something, do it quickly.” I heard a tornado victim who lost everything say on television, ” When you have nothing left to lose anything you do can only be an improvement.” In 2008 Brent Scowcroft summed up the Bush Administration by saying, “Because of the policies of the Bush Administration the United States couldn’t even fight a war that lasted just 3 days without borrowing the money from China to do it.” In 2004 I heard a political pundit say about Kerry and Bush, “When you choose between the lesser of two evils, don’t forget that your choice is still evil.” In 1993 I heard another VP of a company where I worked say, “I don’t want to make the best of a bad situation, I want to avoid a bad situation altogether.” I heard this from the Chairman of National Semiconductor in 1986 and never forgot it: “It’s a tragedy when bad people quit and leave, but it’s worse when they quit and stay.” Be the labor great or small, do it well or not at all.” “If a task is once begun, never leave it till it’s done. “If someone angers you, they control you.” “You don’t have to attend every argument you’re invited to.” It’s your life that sucks.” - Ricky Gervais Quotes and continue to live your life to the fullest.ġ. Treat these quotes as your own life guide, code of conduct in interactions with others because as an adult, you should’ve known by now how important it is to set the right belief and values while we live striving to become a well-rounded, kind people who are bound to leave good legacy. Many quotes are left anonymous, but that doesn’t mean they are not poignant and worth to bear in mind. ![]() Some quotes are from well-known folks among us who has been through things and ultimately have achieved what they believe in. The 17 quotes below has collected are ones of the most brilliant, sometimes sad but true words that are ever uttered about life. In order to do that, it takes time, effort to reflect on people and life, and courage to admit the truth we’ve found. Our lives should be devoted to finding the truth about life and know ourselves better. ![]() This tool also manages a database, "the catalog". Keywords are metadata like any other, but XnViewMP has a specific tool called "Categories" to facilitate their management. Other formats only support certain types of metadata, for example the "raw" formats only support external XMP metadata, put in a companion file, next to the image file. The "JPG" image format and some others support metadata embedded in the image file itself. The XMP standard tends to supplant IPTC, but one can continue to use these two families simultaneously. You can add a lot of information to describe, qualify, or organize and sort the photos, in the form of IPTC and XMP metadata. The EXIF metadata are now reserved for technical information, it is logical not to modify them except for the dates and GPS coordinates which can be created or modified if necessary, using the menu "Tools, Change timestamp" or "Tools, Metadata, Edit GPS data". ![]() There are basically three families, from the oldest to the most recent: EXIF, IPTC, XMP. Metadata can be added to photos to facilitate their management. I had already known how to do that, but if I had found your video before I figured it all out myself it would have probably saved me some time. I will check though.Īnyway, thanks for making the video. I know for sure Crop+Save is in there, not sure if Crop+Save+Next Image is. If you want to do in fullscreen mode and in view mode you will need to change the shortcut/hotkeys on both of those separately as each "switched mode" (browser/view/fullscreen) has it's own set of hotkeys in preferences. ![]() The other option would be to go into keyboard preferences and set up a shortcut to Crop, Save, Next Image. I still prefer the way you show in the video myself. This is slightly faster than doing CTRL-X, CTRL-S, but only slightly so I guess it's a matter of preference. The comments are disabled on the YouTube video linked in your post (crop many images is the link text), I was going to comment that you can also use "Save Selection As." then just hit to save as the same filename (file overwrite confirm must be disabled or you will need to confirm overwrite). Video: Fast way to crop many images using XnView MP Video: How to batch rename and resize using XnView MP ![]() This device is NOT an iPad and if your first thought is, "but I have an iPad" then this isn't for you. It has no browser, no apps to speak of, but an enthusiastic community of hackers and 3rd party projects. It's a dedicated and distraction-free note taker. The reMarkable 2 - This is the second-gen reMarkable. These displays are as close to paper as you can get, today, digitally. It's kind of like an Etch a Sketch, except with electricity rather than a surface covered in aluminum powder. ![]() We can apply negative or positive charge and the black or the white pigments will jump to the top. ![]() How does it work? The simple explanation is that there's tiny capsules of negatively charged black pigment and positively charged white pigment. These one page digital devices promise to act as Infinite Paper.Į Ink is easier on the eyes than OLED and iPads and the like. First the look, and most recently the feel of writing on paper. We seem to be putting a huge amount of technology and work into creating displays to replace paper. The starter Kindle is about $90 and you'll often find sales.įor mostly static content like books or magazines, E Ink is an amazing paper-like technology. They are bright in direct sunlight, and the newer ones have color temperature settings. I'd say 90% of my reading in the last 5 years has been on a Kindle with E Ink. I love my Amazon Kindle and I love its E Ink display. It's going to be interesting to see if it's a fad or if E Ink tablets are here to stay. There's something happening in the E Ink space, somewhat quietly, but consistently. ![]() The created video file is always 0 bytes in size. The 'Cancel' button doesn't work either, have to use the Task Manager to close Xmedia Recode. Please include your ip address, the time you received this message and what you were doing at the time. I have tried waiting upto 5-10 mins for the conversion to initiate, but doesn't work. In Windows you use copy/b file1.mpg+file2.mpg+file3.mpg newfile.mpg In Linux, I use cat: cat file1.mpg file2.mpg file3.mpg > newfile. You can reach us at management (at) e621 (dot) net 7 Answers Sorted by: 26 mpg files are the easiest to join. You will need to contact us to have it removed. If none of the above apply to you, then you have likely been blocked manually after review. At the Format panel, change the output format to MP4. xmrpres files) and delete the rest Copy and rename to suit you. (You may also choose to keep which profiles you want) e.g. First, import your files (including SRT) by dragging it to the main window. Navigate to the install folder, open here or similar: 'C:Program FilesXMedia Recode 64bitProfile' Save one profile set to edit and delete the rest. If you repeatedly see this message you should stop all access attempts and contact us so that the problem can be resolved. Answer (1 of 5): Here’s how you can add subtitles that can be turned on manually (just like MKV) into a MP4 file using XMedia Recode. #4 Something else, probably abusive behavior Please see the wiki page for the API for additional details. The default user agent for many programming languages and libraries have been blocked for abuse.ĭO NOT USE A BROWSER USER AGENT FOR API TOOLS - YOU WILL GET MANUALLY BLOCKED. If you are attempting to use the API you may be seeing this if your user agent is not in line with our user agent policy. ![]() Please contact the author, or find another, more up to date tool. You likely can't resolve this problem yourself, as the application you are using needs to be updated. Do not use some random "documentation" you found on github, it is out of date and incorrect. Please visit the wiki for the most up to date information. If you are making requests to endpoints that are not plurals, then you fall under this category. Check the Large file size option on Handbrake, or the files will not work anywhere. You need to update your application to use the new API urls and response formats. As the result of no shared code between the old and new site, the API changed, both in response format and urls. We updated our codebase quite drastically in March 2020. Something else, I've checked the above 3 and they don't apply to me.Your applications user agent is incorrectly configured.You are using an outdated program that makes use of bad practices or old API endpoints.You have not updated your application to use the new API urls and response formats.There are a few different reasons that you can run into this message: It's great, and probably does what you want! 403 Access Denied - Oh no! If you were using a script/program you found to try and download content, it's likely that the script was what resulted in your request being blocked. ![]() Select All Programs > Accessories > Ease of Access > Windows Speech Recognition.To enable dictation for use in all Windows programs: Speak the text you'd like to transcribe loudly and clearly into the computer or device microphone.Open Evernote for Windows Desktop, select an existing note or create a new one, select the area in your note where you'd like to position your text.Say “Start Listening” or click the microphone button to start the listening mode.Your Mac computer will listen up to 30 second at a time.įor more details, see Apple's article.Your words will appear in the text field. Speak the text you'd like to transcribe clearly into the computer or device microphone.Press the fn key twice or select Edit > Start Dictation. ![]() Click ON to enable Dictation or OFF to disable it.How to set up voice dictation Macĭictation is available for OS X Mountain Lion and later Note: Because speech-to-text is not an Evernote feature, please refer to your computer or device's documentation for more information and resources. Most modern devices support speech-to-text and once you've enabled it, you can start dictating notes into Evernote following the steps below. If you'd prefer to dictate text notes into Evernote, you can use your device's speech-to-text features. Evernote, however, does not convert audio recordings into text nor does it allow you to search for a word mentioned inside the recording. The easiest way to create notes with your voice is to record an audio note. Razer Game Booster, does it really work : r/razer - reddit. It's an interesting alternative to CC Cleaner or Clean Master. Razer Cortex Booster Prime doesnt work on their own razer blades. This can be beneficial when determining if there are any issues that need to be manually rectified. Another interesting technical feature is that users can monitor the performance of their operating system in a real-time scenario. r/pcmasterrace - reddit Razer Cortex review - TechRadar WebFor some of you. This 'auto-boost' feature can be used in conjunction with common gaming portals such as Steam and Origin. In other words, it will run within the background and deactivate any non-essential programs that can slow down your operating system. ![]() Razer Cortex is automatically activated once a gaming session begins. LagoFast - Best Game Booster & Full Functions for Gaming Step 1: Step 2: Step. 1.6K 94K views 1 year ago How to increase framerates in games: Razer Cortex promises to boost FPS in games, as well as optimize graphics settings using machine learning AI algorithms. It can also cause some issues depending on how aggressive you use it. Our advanced machine-learning algorithms have determined the best PC settings for playing top competitive games, so you can choose the game to optimize towards based on your preferred play style. So the effect on a game will be a more stable average framerate (and maybe a slight boost, but don't expect much). Razer Cortex: BOOSTER PRIME uses advanced AIs to optimize your PC settings for the best gaming experience. It essentially frees up RAM and ends some background processes. ![]() It is also very effective during instances when a game is being streamed via an Internet connection. LagoFast - Best Game Booster & Full Functions for Gaming 1. Yes, Cortex does help, but the way it helps may not be as obvious as some people think. Gamers will often choose this package in order to enhance the output their existing Windows processor as well as to free up additional memory that would have otherwise remained untapped. ![]() Razer Cortex is a software package that boosts your device's memory intended to maximize the performance of operating systems. Softonic review Gaming software to enhance the performance of operating systems As indicated by Razer itself, Cortex consequently closes down overall processes at whatever point you boot a game. ![]() However, with the recent announcement of the 80/20 purse split for Fury’s fight with WBC mandatory Dillian Whyte, it’s now unclear if Ruiz is still an option for the Gypsy King’s next fight in March. WBC heavyweight champion Tyson Fury’s promoter Bob Arum recently mentioned that Ruiz was one of two fighters that he’s negotiating with for his next fight. announced on his social media site on Sunday that he’ll be turning to the ring soon, with a fight date to be revealed soon. I’m ready to get my belts back, not just my belts, I’m coming for you Tyson Fury – I need that WBC.Former heavyweight champion Andy Ruiz Jr. I would always do it the wrong way, use plastic, try to lose weight at the last minute, drain myself. "In my other fights I used to weigh 270lbs, 280lbs and I would have to lose 20lbs just to get in my weight. Now is the beginning to see the real and new Andy Ruiz Jr. I was depressed, I was mad at myself because I knew I should’ve trained, I knew I should’ve done better in my last fight, but it’s never too late. After my fight against Anthony Joshua, my defeat in Saudi Arabia, I gained to like 310lb. “I’m tired man, you see me do all those f***ing drills? But, like I said, all this hard work and dedication is gonna pay off," Ruiz Jr said before his previous meeting with Arreola. Ruiz Jr previously admitted he ballooned up to 22 stone following his victory over Joshua, but believes fans will now see him return in peak condition. What do you make of Andy Ruiz Jr's weight loss? Let us know in the comments section belowĪndy Ruiz Jr announces next fight after being criticised for not training by Canelo Alvarez Despite his lacklustre performance, he looked much leaner during that rematch after putting in a place a strict diet under the guide of trainer Eddy Reynoso. ![]() He made his ring return last year but looked unconvincing in a points victory over Arreola, where he was forced to recover from being dropped early on. Ruiz then took a two-year hiatus from the sport which was mostly down to the adverse effects of the coronavirus pandemic. He looked out of shape for the rematch staged in the Middle East and was unable to get near Joshua, who delivered a slick display to win back the unified crown. The Mexican burst on to the scene with a sensational stoppage of Joshua six months previously before piling on a significant amount of weight. Fans commented in their droves about his physique with one remarking: "Who is that? No way that’s Andy Ruiz."Īnother added: "Bro is he even heavyweight anymore?" One even confused him for another person: "Damn he don’t even look like the same person." Ruiz Jr has faced a period of relative inactivity since losing his mega-money rematch with Joshua in Saudi Arabia. Ruiz Jr can be seen in the footage working on his posture during a session, where he looks significantly lighter than in his previous victory. ![]() However he is now preparing for the challenge of Ortiz in September, and has shown off his remarkable weight loss. Ruiz Jr was rumoured to be stepping back in the ring with Tyrone Spong in July as part of boxing promotion Triller's latest fight card. The Mexican hasn't fought since labouring to victory against Chris Arreola last May in what was his first fight since losing to Anthony Joshua in 2019. Andy Ruiz Jr has shown off a new trimmed physique ahead of his heavyweight return against Luis Ortiz. ![]() So give it your best shot, because in this city, only the strong survive." So, when can fans anticipate the return of said "heartbreaks" and "hook-ups"? Read on for all the details on Season 11. In the world of Love & Hip Hop, nothing is sacred. The popular reality show follows a group of people involved in the hip-hop industry in some capacity from managers to performers to partners of those in the industry. ![]() The cost of fame is high and somebody's always paying the price. 02:15 Safaree's Mom Wants To Pick His Next Girlfriend HighlightS8 Safaree gets advice on how to find the right woman from his mom and sisters. Since the first season of VH1's 'Love & Hip Hop: New York' debuted in 2011, viewers have been nearly obsessed with the cast of likable characters. Some families experienced new beginnings while other relationships came to end. Reality TV lovers are anxiously awaiting the return of 'Love & Hip Hop: New York' after the 10th season of the VH1 series ended in March 2020. Lampkin continued, "There's been hook-ups and heartbreaks. It's been almost ten years and a lot has happened." ![]() Dubbed as riveting, addictive, bawdy and hilarious, and a. The tv series has been a staple on the network because of its crazy acceptance among fans. But you know, you should never say never. Branded as VH1’s groundbreaking reality title, Love & Hip Hop: New York is the original installment from the channel’s powerhouse Love & Hip Hop franchise. But when it all fell apart, I chose to walk away. From fights to proposals, we put it all out there. Theyve supported their men on the road to hip-hop stardom, and the women featured in this. "Jim and I, we were the day ones, we started this thing. Being home brings back all sorts of memories," said actor Chrissy Lampkin to kick off season 10 in 2019, after the Season 1 and 2 cast member skipped out on "LHHNY" for seven seasons (via The Cinemaholic). "They say that when you come home, everything looks and feels the same, and you realize what's changed is you. |
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